Clinical Trial Intelligence

The neutral data layer for clinical execution

History-aware, append-only, query-safe. Nexum connects sponsors, trials, sites, and outcomes into a unified relationship spine—built to plug into research pipelines with institutional reliability.

Explore Live Data → View Documentation

0

Events Tracked

0

Uptime

0

Sync Latency

Append-only ledger Real-time sync Stable schemas GraphQL + REST Version controlled Audit trails Query-safe views Institutional SLA Zero data loss PostgreSQL wire protocol Append-only ledger Real-time sync Stable schemas GraphQL + REST Version controlled Audit trails Query-safe views Institutional SLA Zero data loss PostgreSQL wire protocol

Developer Experience

First query in under 5 minutes

Direct PostgreSQL access, REST, and GraphQL endpoints. Use your existing tools—no proprietary SDK required. Every query is reproducible, every result is versioned.

GET /v1/trials?status=recruiting&phase=3

GET /v1/events?trial_id=NCT05847392

POST /v1/query { "sql": "SELECT ..." }

WSS /v1/stream/events

query.py

import nexum
 
# Connect with your API key
client = nexum.connect("nx_live_...")
 
# Query active Phase III oncology trials
trials = client.query(
  phase="III",
  status="recruiting",
  condition="NSCLC"
)

Built Different

Infrastructure-grade clinical data

Unlike vendor-locked platforms, Nexum gives you direct database access with a stable schema, full version history, and reproducible queries.

01

Append-Only Architecture

Every update becomes an immutable event. Full audit trail, point-in-time queries, zero data loss.

02

Relationship Graph

Connect sponsors, sites, investigators, and outcomes. See the complete clinical execution network.

03

Stable Query Interface

No breaking schema changes. Save queries, add parameters, cache results. Built for reproducibility.

04

Real-Time Sync

Sub-2-minute latency from public registries. WebSocket updates for live dashboards.

05

API-First Design

PostgreSQL wire protocol, REST, and GraphQL. Use your existing tools and workflows.

06

Institutional SLA

99.9% uptime guarantee. Dedicated support. On-premises deployment options available.

Ready to build on clinical intelligence?

Join research teams using Nexum to power reproducible, query-safe clinical data pipelines.

Request Access → Explore Live Data

INFRASTRUCTURE

API-first clinical trial event ledger

Nexum is built as infrastructure: append-only events, deterministic diffs, and provenance you can audit. No opinions in the core—just query-safe truth with memory.

🔗

7,180

Sponsor-Site Relationships

Track which sponsors work with which sites across all trials

📊

420

Sponsor Performance Profiles

Due diligence data on site selection quality and trial success rates

🏥

29,423

Sites with Trial History

Complete trial history, completion rates, and performance metrics

⚡ Premium Intelligence

🔓 Unlock Full API Access

Get unlimited queries, complete site data, premium intelligence views, and enterprise support

29,423

Total Sites

420+

Sponsor Profiles

∞

Queries/Month

Starting at $500/month • 7-day free trial included

                            SELECT sponsor_lead, total_trials, avg_site_completion_rate

                            FROM v_sponsor_performance

                            ORDER BY total_trials DESC

                            LIMIT 10;

Results: 0 rows

Click "Run Query" to see results

✓ Stable schemas

✓ Pagination

✓ Rate limits

✓ Audit-ready

Need full access?

Unlimited queries, all 29k sites

From $500/month

Documentation

ENDPOINTS

Trials, events, sponsors, sites

                        /v1/trials

                        /v1/events

                        /v1/sponsors

                        /v1/sites

SCHEMA

Intelligence Views

                        v_sponsor_performance

                        v_sponsor_site_network

                        v_site_trial_history

                        v_high_risk_sponsors

INTEGRATIONS

Export & sync

                        CSV export

                        JSON webhooks

                        Snowflake/BigQuery

See Live Data →

Use Cases

Intelligence for every stakeholder

From oncology researchers to hedge fund analysts—see how teams use Nexum to monitor trials, track drift, and identify market signals.

Track 2,847 active oncology trials across Phase II–III. Monitor enrollment velocity, completion drift, and sponsor performance. Updated daily from ClinicalTrials.gov snapshots.

🎯 Phase II–III Focus 📊 2,847 Active Trials 🔄 Daily Updates 🔥 12 High-Risk Alerts

Active Trials

2,847

↑ 124 vs. last month

Avg Completion Drift

187d

↓ 12d vs. Q4 2024

High-Risk Trials

342

↑ 18 this week

Enrollment Rate

67%

→ Stable

Weekly Trial Starts by Phase (Last 6 Months)

Placeholder — switches with filters above

Status Distribution

Placeholder — switches with filters above

High-Risk Trials (Delayed >180 Days)

Trials with significant completion date drift

Trial ID	Sponsor	Indication	Phase	Original Date	Current Est.	Drift	Risk
NCT05847392	BioNova	NSCLC	Phase III	Dec 2025	Aug 2026	+245d	HIGH
NCT04123987	Novartis	Melanoma	Phase II	Mar 2026	Sep 2026	+189d	HIGH
NCT05234567	Roche	Breast Cancer	Phase III	Jun 2026	Nov 2026	+156d	MEDIUM

⚠️ Critical Alerts

Critical: Accelerating Drift — NCT05847392

Drift velocity increased from +6d/week to +12d/week in last 30 days. At current rate, completion pushed to Q1 2027 (vs. original Q4 2025). Recommend sponsor review.

Forecast Alert: 34 Trials Likely to Cross 365d Drift Threshold

Based on current velocity trends, 34 active trials will exceed 1-year delay by Q3 2026. 18 are Phase III (potential material impact on sponsor timelines).

Comparative performance metrics across top sponsors. Track portfolio health, execution consistency, and competitive positioning in real-time.

🏢 Top 50 Sponsors 📊 Portfolio Analytics ⚡ Real-time Rankings

Tracked Sponsors

127

Top 50 by trial volume

Best Performer

AZ

Avg -12d drift

Highest Drift

NVS

Avg +87d drift

Portfolio Health

72%

Trials on schedule

Top Sponsors by Portfolio Size

Active oncology trials by sponsor

Roche (234)

Novartis (198)

BMS (187)

Pfizer (165)

Merck (147)

Execution Performance Score

Composite metric: drift + enrollment + completion

Higher score = Better execution

Sponsor Performance Leaderboard

Ranked by execution metrics

Rank	Sponsor	Active Trials	Avg Drift	On-Time %	Performance
1	AstraZeneca	143	-12d	87%	EXCELLENT
2	Roche	234	+18d	78%	GOOD
3	Merck	147	+34d	72%	GOOD
4	Novartis	198	+87d	58%	FAIR

Deep-dive into completion date drift patterns. Track velocity, forecast future delays, and identify systemic execution issues before they compound.

📈 Drift Velocity Tracking 🔮 ML-Powered Forecasts ⚠️ Early Warning System

Median Drift

+89d

↓ 15d vs. last quarter

Trials >1yr Delayed

67

↑ 12 this month

Accelerating Drift

23

Velocity >7d/week

Forecast Accuracy

84%

30-day predictions

Drift Distribution by Phase (Last 12 Months)

Completion date changes over time

Average drift trending down over time

Drift by Indication

Which indications delay most?

CRC

NSCLC

Melanoma

Breast

Accelerating Drift Watch List

Trials with increasing drift velocity

Trial ID	Sponsor	Current Drift	Velocity	30d Forecast	Alert Level
NCT05847392	BioNova	+245d	+12d/wk	+293d	CRITICAL
NCT04987234	MedTech Inc	+178d	+9d/wk	+214d	CRITICAL
NCT05123456	Novartis	+134d	+7d/wk	+162d	HIGH

Actionable trial intelligence for hedge funds and biotech investors. Track material events, catalyst timelines, and competitive positioning. Detect alpha-generating signals 5-10 days before market pricing.

💹 Trading Signals 📅 Catalyst Calendar 🔔 Material Events 📊 Competitive Intel

Material Events (7d)

23

↑ 7 high-impact

Catalyst Events (30d)

67

→ On schedule

Competitive Shifts

12

↑ NSCLC heating up

Alpha Opportunities

8

↑ 3 new this week

🔥 High-Impact Events (Last 7 Days)

Material trial events with market implications

Date	Event Type	Sponsor (Ticker)	Trial	Signal	Impact
Feb 4	Major Delay	BioNova (BNVA)	NCT05847392	🔻 Bearish	HIGH
Feb 3	Early Completion	Novartis (NVS)	NCT04123456	🔺 Bullish	MEDIUM
Feb 2	Enrollment Complete	Merck (MRK)	NCT05234789	🔺 Bullish	MEDIUM
Feb 1	Trial Terminated	SmallCap Bio (SMCP)	NCT04987234	🔻 Bearish	HIGH

📅 Upcoming Catalysts (Next 30 Days)

Forecasted trial milestones with confidence intervals

Est. Date	Catalyst	Sponsor	Trial	Indication	Confidence
Feb 15 ±7d	Primary Completion	Roche	NCT04556789	Melanoma Phase III	High (92%)
Feb 22 ±10d	Enrollment Target	AstraZeneca	NCT05123987	NSCLC Phase II	Medium (74%)
Mar 5 ±14d	Study Completion	BMS	NCT04789234	CRC Phase III	Medium (68%)

💡 Alpha Opportunities

Pattern: BioNova (BNVA) — Multiple Trial Delays

Signal: 3 concurrent trials delayed in Q1 (avg +6 months). Stock hasn't priced this in yet.
Thesis: Pipeline delays → revenue push-out → potential downside catalyst when disclosed in Q1 earnings (Mar 12).
Action: Monitor for official disclosure. Potential short opportunity if delays not yet public.

Competitive Intel: NSCLC Landscape Shifting

Observation: AstraZeneca accelerating 4 NSCLC trials (avg -23d drift) while Novartis slowing (avg +87d drift).
Implication: AZ potentially 6-9 months ahead in readouts → first-mover advantage in next-gen NSCLC market.
Action: Long AZ vs. short NVS pair trade opportunity on timeline divergence.

See what Nexum can do for your use case

From trial monitoring to market intelligence—Nexum provides the infrastructure for clinical data insights.

Request Access → Explore Live Data

Live Ingestion

Every clinical change, captured.

Nexum is an append-only ingestion ledger for clinical trials—turning public registry updates into queryable clinical events with full history and provenance.

Total Trials

—

Unique oncology trials ingested

Total Events

—

Append-only event records

Last 24 Hours

—

Trials fetched in the last day

Ingestion Watermark

—

Last fetch: —

Top Conditions

Most tracked conditions

Phase Distribution

Trials by phase

Ingestion Rate (7 Days)

Daily trial ingestion

Recently Ingested Trials

Last 20 trials added to the system

Loading recent trials...

Request Access

Get started with Nexum

For now, explore our Live Data preview. When you're ready, we'll add a waitlist and API keys for full platform access.

Open Live Data View Platform

Sites Directory

29,423 Clinical Trial Sites

Search top-performing research sites by name, location, or specialty

29,423

Total Sites

120+

Countries

3,200+

Active Trials

78.5%

Avg Completion Rate

Showing 50 of 29,423 sites • Free tier limited to top 50

Site	Trials ↕	Completion ↕	Active	Specialty	Score ↕
⏳ Loading sites...

Need programmatic access?

Query all 29k sites, filter by any criteria, export data

The neutral data layer for clinical execution

First query in under 5 minutes

Infrastructure-grade clinical data

Append-Only Architecture

Relationship Graph

Stable Query Interface

Real-Time Sync

API-First Design

Institutional SLA

Ready to build on clinical intelligence?

API-first clinical trial event ledger

🔓 Unlock Full API Access

Documentation

Intelligence for every stakeholder

⚠️ Critical Alerts

💡 Alpha Opportunities

See what Nexum can do for your use case

Every clinical change, captured.

Top Conditions

Phase Distribution

Ingestion Rate (7 Days)

Get started with Nexum

29,423 Clinical Trial Sites

Want to See Which Sponsors Use These Sites?

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